Neurodigitech (NDT) is dedicated to 1) Neurohistological and neuropathological services of the central nervous system (CNS), 2) Neural staining kits, 3) High-throughput digital microscopic imaging and stereology-based quantitative morphology, and 4) GLP and non-GLP studies. NDT is a global laboratory service company, dedicated to providing time- and cost-effective brain research products and services for the preclinical studies of the CNS, focused on various types of neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, Huntington’s diseases, ischemic stroke, and motor neuron disease (MND), including the Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease as well as the spinal cord injury (SCI).
Neurohistology service
NDT provides the most reliable histological service, including cryo-and paraffin-based sectioning with standard histological stains (Cresyl violet, Hematoxylin, and Eosin stain or H & E, Methyl green, Neutral red, Safranin, etc), special stains (Golgi-Cox impregnation, Gallyas silver stain, deOmos Amino Cupric silver stain, etc), and immunofluorescence and immunoperoxidase of the biomarkers for basic and neuro-histopathological research. The deliverables include: 1) serial-mounted slides with labels in boxes and/or representative digital images of the region(s) of interest and morphological analysis (upon request). With extensive research experience, NDT also helps our customers validate and develop the most cost-effective experimental designs and protocols. Technical support is always available throughout the course of the study.
Neural staining kits
With increasing demands in time and cost for research projects, the affordable, user-friendly staining kits play an important role for researchers to achieve their scientific breakthrough. NDT is dedicated to providing the quick delivery of high-quality, ready-to-use neurohistological staining packages, including the proprietary FD Apop™, FD NeuroApop™, FD NeuroSilver™, FD Rapid GolgiStain™, FD Multi RapidStain™FD Rapid TimmStain™ kits. The most recent new product, GolgiChrome™ kit is the first modified and commercialized version of the Golgi-Cox method that allows the simultaneous staining of the metal/silver impregnation and immunohistochemistry. This innovated method will help researchers able to simultaneously visualize (a) the structural detail, (b) the antigen’s characterization, (c) the anatomical interaction between discrete neuronal elements, and (d) the 3D reconstruction and modeling of the central nervous system (CNS).
Digital microscopic imaging and morphometric analysis
Using the state-of-the-art digital imaging and unbiased stereology-based morphological analysis protocol, including 2-D and 3-D digitized microscopic and MRI imaging visualization and reconstruction programs, we help our customers streamline the processes of digital data acquisition and high-standard quantitative analysis. We also provide consultations for peer-reviewed publications. NDT also welcomes scientific collaborations since we believe Customer's comments can always help us improve the quality of our services.
Preclinical CRO service
The NDT teams in specialized in both non-GLP and GLP compliant pre-clinical assessments of CNS disease therapeutics using a variety of biomarkers, including histology, immunohistochemical and histochemical methods. In particular, NDT is dedicated to custom-designed neuropathological assessments for the neurodegenerative diseases, such as Alzheimer's, Parkinson's, ALS, and brain insults (strokes and brain tumors) and Human neural stem cell and small molecule biomarker programs for preclinical studies of animal models upon request. NDT helps our clients develop the most time- and cost-effective study design and analytical methods with digital imaging platform with unbiased, computerized morphological analysis to render most reliable scientific results.
Terms and Conditions
For quality assurance of our service, it is recommended that you discuss with us for preferred perfusion protocol and histology and/or immunolabeling protocols.
It is suggested that you use Gel-coated microscopic slides for tissue mounting and 0.17um-thick coverslips.
A 15% of the fee will be due upon authorization of the study; and the remaining fee will be due upon delivery of study results.
Progress of the service is contingent upon staining quality of tissues, operated by the independent contractor.
Should early termination occur, Neurodigitech will prorate the cost incurred and invoice the Sponsor. The first portion of the fee is non-refundable.
Neural Gallery
